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| Fjord Technology: Home-grown Technology to Fight Cancer |
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| Cervical cancer is the fifth most deadly cancer in women worldwide. It affects about 1 per 123 women per year and kills about nine per 100,000 per year. In Malaysia, cervical cancer is the second most common cancer disease with 2,500 new cases diagnosed every year. However, unlike most other common cancers, it has been observed to occur as a result of Human Papillomavirus (HPV) infections. The Papanicolaou test, or Pap smear, and its widespread use for cervical cancer screening have been credited with dramatically reducing the incidence and mortality of cervical cancer in developed countries. | ||||||||||
| Anticipating the gap in women healthcare in developing countries, a Malaysian company is pioneering the market in providing an affordable and more efficient screening method for cervical cancer. Developed, produced via its own biotechnological know how and marketed in Malaysia and selected Asian countries, the Liqúi-Smear™ Pap Test by Fjord Technology would revolutionize the medical diagnostic market in the region. | ||||||||||
| The Pap Smear test itself is generally painless. A qualified doctor or nurse will do an internal examination by gently taking cells from the surface of the cervix speculum using a spatula and an endocervical brush. The cells are then placed on a glass slide, stained using the Papanicolaou technique, and sent to a laboratory for a microscopic examination by a specially trained and qualified cytotechnologist. The accuracy of conventional cytology report allows 92% specificity and 72% accuracy. However, current techniques are typically limited by interference of mucus and blood during the retrieval process, as well as the sampled cells being not a good representation of the overall condition. | ||||||||||
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| Fig.
1 Comparison of a conventional Pap Smear (L) with Fjord Technology's
Liquid Based Cytology (R)
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| The
screening of cells is typically labour intensive, and may result in
technicians failing to provide an accurate diagnosis, as a certain percentage
of Pap smear slides are obscured by blood, mucus and inflammation, rendering
the slides being unsatisfactory for diagnosis. In fact, in the United
States, physicians who fail to diagnose cervical cancer from a Pap smear
have been convicted of negligent homicide. More efficient and effective
techniques have been devised to address the limitations of conventional
Pap smear. Among them, Liquid based monolayer cytology. The samples
are placed into a vial containing a liquid medium which preserves the
cells and prepares the cells for processing.
“The
beauty of the Fjord Technology’s Liqúi-Smear™ Pap
Test is through it having European beauty, American quality and Asian
prices,” quipped Managing Director, Mr K.M. Chin. “We have
been able to, based on our own liquid based cytology formulation, utilize
state-of-the-art cell separation, preservation and imaging technologies
to produce an automated system which will allow the diagnosis process
to be fully streamlined.” | ||||||||||
Founded
in 2003 by medical diagnostic industry veteran, Mr. K.M. Chin and his
engineer partner, Mr. Nicholas Cheong, Fjord encompasses the experience
Mr. K.M. Chin has accumulated working in the industry for over 20 years
locally and abroad, with leading medical diagnostic multinationals.
He has observed the high costs of many other diagnostic kits result
in a prohibitive environment for cervical screening which is not being
enforced in the country, and hence wanted to resolve it by providing
a better alternative to the current available products and enhancing
on it. Today, Fjord Technology’s Liqúi-Smear™ System
is being utilized by many pathology laboratories across the country.
It also has customers across the ASEAN region, including Indonesia,
Philippines and Thailand.
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Fig.
2 Mr. K.M. Chin, Fjord’s MD with visitor to Fjord Exhibit at the
recent 24th World Congress of Pathology and Lab Medicine
| Fig.
3 Liqúi-Smear Processor and consumables
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On its future developments, Fjord is setting its sights on some lofty aims. Among them, Fjord has applied for Bionexus status, in hopes of being recognized for its groundbreaking work. It is also open to partnering new strategic investors who can assist financially to accelerate its growth plans. Similarly, it hopes to cinch the market-leader place in the region, as well as develop its platform into various other forms of diagnostics while enhancing value. Fjord is also looking into the prospects of Mesdaq listing beyond the next 24 months as the Malaysian Government pushes towards biotechnology development in its recent 2005 Biotechnology Policy.
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| By K. C. Liew for MABIC | ||||||||||
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